Article
Strategies to overcome drug resistance of receptor tyrosine kinaseaddicted cancer cells.
Current medicinal chemistry - 1 Jan 2014
Maina Flavio
Abstract excerpt
The use of agents capable of impairing RTK function is gaining prominence for their effectiveness against the tumorigenic program driven by oncogenic RTK activity in a wide range of cancer cells. Having this valuable resource in hand for molecularly targeted anticancer therapies, it is mandatory to understand how to use these agents properly for combined treatments in order to maximize clinical efficacy. The...
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