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The Merkel Cell Polyomavirus Minor Capsid Protein

22 Aug 2013

Abstract excerpt

The surface of polyomavirus virions is composed of pentameric knobs of the major capsid protein, VP1. In previously studied polyomavirus species, such as SV40, two interior capsid proteins, VP2 and VP3, emerge from the virion to play important roles during the infectious entry process. Translation of the VP3 protein initiates at a highly conserved Met-Ala-Leu motif within the VP2 open reading frame. Phylogenetic...

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PMID: 23990782
DOI: 10.1371/journal.ppat.1003558

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