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Article

Targeted therapy for breast cancer.

The American journal of pathology - 1 Oct 2013

Mohamed Ali, Krajewski Kenneth, Cakar Burcu, Ma Cynthia X

Abstract excerpt

Breast cancer is a heterogeneous group of diseases that are clinically subdivided as hormone receptor-positive, human epidermal growth factor receptor 2-positive (HER2(+)), and triple-negative breast cancer, to guide therapeutic interventions. Agents that target estrogen receptor (ER) and HER2 are among the most successful cancer therapeutics. However, de novo or acquired resistance is common, despite the...

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PMID: 23988612
DOI: 10.1016/j.ajpath.2013.07.005

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