Article
The toll and Imd pathways are not required for wolbachia-mediated dengue virus interference.
Journal of virology - 1 Nov 2013
Rancès Edwige, Johnson Travis K, Popovici Jean, Iturbe-Ormaetxe Iñaki, Zakir Tasnim, Warr Coral G, O'Neill Scott L
Abstract excerpt
Wolbachia blocks dengue virus replication in Drosophila melanogaster as well as in Aedes aegypti. Using the Drosophila model and mutations in the Toll and Imd pathways, we showed that neither pathway is required for expression of the dengue virus-blocking phenotype in the Drosophila host. This pr...
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