Article
Genome architecture is a selectable trait that can be maintained by antagonistic pleiotropy.
Nature communications - 1 Jan 2013
Avelar Ana Teresa, Perfeito Lília, Gordo Isabel, Ferreira Miguel Godinho
Abstract excerpt
Chromosomal rearrangements are mutations contributing to both within and between species variation; however their contribution to fitness is yet to be measured. Here we show that chromosomal rearrangements are pervasive in natural isolates of Schizosaccharomyces pombe and contribute to reproductive isolation. To determine the fitness effects of chromosome structure, we constructed two inversions and eight...
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