Article
Biological treatments: new weapons in the management of monogenic autoinflammatory disorders.
Mediators of inflammation - 1 Jan 2013
Vitale Antonio, Rigante Donato, Lucherini Orso Maria, Caso Francesco, Muscari Isabella, Magnotti Flora, Brizi Maria Giuseppina, Guerrini Susanna, Patti Maria, Punzi Leonardo, Galeazzi Mauro, Cantarini Luca
Abstract excerpt
Treatment of monogenic autoinflammatory disorders, an expanding group of hereditary diseases characterized by apparently unprovoked recurrent episodes of inflammation, without high-titre autoantibodies or antigen-specific T cells, has been revolutionized by the discovery that several of these conditions are caused by mutations in proteins involved in the mechanisms of innate immune response, including components...
Topics
- Acne Vulgaris
- Anemia, Dyserythropoietic, Congenital
- Arthritis
- Arthritis, Infectious
- Biological Products
- Cranial Nerve Diseases
- Cryopyrin-Associated Periodic Syndromes
- Familial Mediterranean Fever
- Fever
