Article
Expansion of multipotent stem cells from the adult human brain.
PloS one - 1 Jan 2013
Murrell Wayne, Palmero Emily, Bianco John, Stangeland Biljana, Joel Mrinal, Paulson Linda, Thiede Bernd, Grieg Zanina, Ramsnes Ingunn, Skjellegrind Håvard K, Nygård Ståle, Brandal Petter, Sandberg Cecilie, Vik-Mo Einar, Palmero Sheryl, Langmoen Iver A
Abstract excerpt
The discovery of stem cells in the adult human brain has revealed new possible scenarios for treatment of the sick or injured brain. Both clinical use of and preclinical research on human adult neural stem cells have, however, been seriously hampered by the fact that it has been impossible to passage these cells more than a very few times and with little expansion of cell numbers. Having explored a number of...
Topics
- Adult
- Biomarkers
- Brain
- Cell Culture Techniques
- Cell Differentiation
- Clone Cells
- Dopaminergic Neurons
- Gene Expression Regulation
- Humans
- Karyotyping