Article
Tissue genotyping of 37 in situ and invasive cervical cancer with a concomitant negative HC2 HPV DNA test.
Journal of lower genital tract disease - 1 Jan 2014
Igidbashian Sarah, Schettino Maria Teresa, Boveri Sara, Barberis Massimo, Sandri Maria Teresa, Carinelli Silvestro, Cannone Maria, Sideri Mario
Abstract excerpt
OBJECTIVE: The rare occurrence of histology-proven cervical intraepithelial neoplasia grade 3 (CIN 3) or invasive cancer with a negative HC2 result is known. Tissue blocks of 37 cases of histology-diagnosed CIN 3+ with a concomitant negative HC2 test were genotyped to investigate the human papillomavirus (HPV) status within the lesion. METHODS: We considered 1,976 cervical excision specimens performed with...
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