Article
Identification of one or two α-globin gene deletions by isoelectric focusing electrophoresis.
American journal of clinical pathology - 1 Sept 2013
Agarwal Archana M, Nussenzveig Roberto H, Hoke Carolyn, Lorey Thomas S, Greene Dina N
Abstract excerpt
OBJECTIVES: To investigate the utility of isoelectric focusing electrophoresis (IEF) for identifying patients with α-thalassemia, which results from the deletion of 1 or more of the α-globin genes. METHODS: Samples were selected based on their hemoglobin H (HbH) concentration observed using IEF. The samples were analyzed for the most common α-globin gene deletions using molecular analysis. RESULTS: α-Globin gene...
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