Article
Segregation of a latent high adiposity phenotype in families with a history of type 2 diabetes mellitus implicates rare obesity-susceptibility genetic variants with large effects in diabetes-related obesity.
PloS one - 1 Jan 2013
Jenkins Arthur B, Batterham Marijka, Samocha-Bonet Dorit, Tonks Katherine, Greenfield Jerry R, Campbell Lesley V
Abstract excerpt
BACKGROUND: We recently reported significantly greater weight gain in non-diabetic healthy subjects with a 1(st) degree family history (FH+) of type 2 diabetes mellitus (T2DM) than in a matched control group without such history (FH-) during voluntary overfeeding, implying co-inheritance of susce...
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