Article
Genetic characterization of Plasmodium falciparum allelic variants infecting mothers at delivery and their children during their first plasmodial infections.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Dec 2013
Dechavanne Célia, Pierrat Charlotte, Renard Emmanuelle, Costes Bruno, Martin Natacha, Ladekpo Rodolphe, Ahouangninou Claude, Alvarez Violeta Moya, Huynh Bich Tram, Garcia André, Migot-Nabias Florence
Abstract excerpt
INTRODUCTION: Infants born to mothers with placental malaria at delivery develop Plasmodium falciparum parasitemia earlier than those born to mothers without placental infection. This phenomenon may be explained by the development of immune tolerance due to exposure to P. falciparum antigens in utero. The hypothesis of this study is that this increased susceptibility might be related to infections by parasites...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.