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Article

HLA-DQa allelic frequencies detected with PCR in a variety of human populations.

Gene geography : a computerized bulletin on human gene frequencies - 1 Dec 1992

Kurth J H, Bowcock A M, Erlich H A, Cavallisforza L L

Abstract excerpt

Polymerase chain reaction (PCR) amplification and oligonucleotide probe hybridization may be used to detect DNA polymorphisms rapidly in large samples. In this study, 475 individuals from thirteen human populations were allelotyped at the human leukocyte antigen (HLA) DQa (DQA1) locus. A 242 or 239 bp fragment was amplified from each individual's DNA. Each of six alleles was detected by hybridization to allele...

Topics

Alleles
Gene Frequency
HLA-DQ Antigens
HLA-DQ alpha-Chains
Heterozygote
Humans
Polymerase Chain Reaction

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1339494

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FST

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1339494-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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