Article
The HHEX gene is not related to congenital heart disease in 296 Chinese patients.
World journal of pediatrics : WJP - 1 Aug 2013
Deng Xiao-Peng, Zhao Li-Xi, Wang Bin-Bin, Wang Jing, Cheng Long-Fei, Cheng Zhi, Suo Pei-Su, Li Hui, Ma Xu
Abstract excerpt
BACKGROUND: The hematopoietically expressed homeobox (HHEX) gene is an important determinant of mammalian heart development. This study aimed to identify the potential mutations of the gene in Chinese patients with congenital heart disease (CHD). METHODS: We collected 296 CHD patients and 200 controls, and classified the cardiac deformities. Then we conducted sequence analyses of the HHEX gene in those patients....
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