Article
Macrophage phenotype in the mammary gland fluctuates over the course of the estrous cycle and is regulated by ovarian steroid hormones.
Biology of reproduction - 1 Sept 2013
Hodson Leigh J, Chua Angela C L, Evdokiou Andreas, Robertson Sarah A, Ingman Wendy V
Abstract excerpt
The mammary gland undergoes development and regression over the course of the ovarian cycle under the regulation of ovarian hormones. Macrophages are implicated as local mediators of this tissue remodeling and may also affect immune surveillance and tumor incidence. To investigate cycle-related changes in macrophage phenotype, mammary gland cells from naturally cycling Cfms-Gfp mice recovered at estrus,...
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