Article
[Genotype of thalassemia genes and the polymorphism of β- globin gene in Cantonese].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Jul 2013
Liu Ling, Jiang Wei-ying, Xu Shi-yan, Chen Juan, Chen Lu-ming, Tian Qiu-hong, Wang Ji-cheng
Abstract excerpt
OBJECTIVE: To understand the genotype of α and β-globin, as well as the polymorphism of β-globin gene in Cantonese in recent years, and to provide an effective genetic diagnosis for thalassemia (thal). METHODS: The single-tube complex PCR was used to detect 3 types of deletional α-thal, reverse dot blotting (RDB)/PCR to detect 3 kinds of undeletional α-thal-αCS, αQS, αWSand 18 kinds of β-thal mutations which were...
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