Article
Genetic basis of aminoglycoside resistance following changes in aminoglycoside prescription patterns.
Journal of chemotherapy (Florence, Italy) - 1 Aug 2013
Kosmidis Chris, Giannopoulou Maria, Flountzi Anastasia, Markogiannakis Antonis, Goukos Dimitris, Petrikkos George, Daikos George L, Tzanetou Konstantina
Abstract excerpt
Aminoglycosides (AG) offer an important therapeutic option for the treatment of infections caused by multiresistant Enterobacteriaceae. We observed a change in AG usage patterns in our institution between 1997 and 2006, namely a reduction in use of all AG except amikacin. We studied the changes in AG susceptibility rates in these time periods and correlated with prevalence of different molecular resistance...
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