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Article

Bone and cartilage formation in diffusion chambers by subcultured cells derived from the periosteum.

Bone - 1 Jan 1990

Nakahara H, Bruder S P, Haynesworth S E, Holecek J J, Baber M A, Goldberg V M, Caplan A I

Abstract excerpt

Periosteal cells were enzymatically isolated from the tibiae of young chicks, introduced into cell culture, allowed to reach confluence, and subcultured. The freshly isolated or subcultured cells were loaded into diffusion chambers and implanted into the peritoneal cavity of athymic mice to test their osteo-chondrogenic potential in a contained in vivo location. Freshly isolated periosteal cells formed both bone...

Topics

Animals
Antibodies, Monoclonal
Antibody Specificity
Bone Development
Cartilage
Cell Division
Cells, Cultured
Chickens
Diffusion Chambers, Culture
Fibroblasts
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Nude

Muscles

Periosteum

Phenotype

Source

Identifiers

PMID: 2390376
DOI: 10.1016/8756-3282(90)90212-h

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2390376-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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