Identification of HKDC1 and BACE2 as genes influencing glycemic traits during pregnancy through genome-wide association studies.

doi:10.2337/db12-1692

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Identification of HKDC1 and BACE2 as genes influencing glycemic traits during pregnancy through genome-wide association studies.

Diabetes - 1 Sept 2013

Hayes M Geoffrey, Urbanek Margrit, Hivert Marie-France, Armstrong Loren L, Morrison Jean, Guo Cong, Lowe Lynn P, Scheftner Douglas A, Pluzhnikov Anna, Levine David M, McHugh Caitlin P, Ackerman Christine M, Bouchard Luigi, Brisson Diane, Layden Brian T, Mirel Daniel, Doheny Kimberly F, Leya Marysa V, Lown-Hecht Rachel N, Dyer Alan R, Metzger Boyd E, Reddy Timothy E, Cox Nancy J, Lowe William L

Abstract excerpt

Maternal metabolism during pregnancy impacts the developing fetus, affecting offspring birth weight and adiposity. This has important implications for metabolic health later in life (e.g., offspring of mothers with pre-existing or gestational diabetes mellitus have an increased risk of metabolic disorders in childhood). To identify genetic loci associated with measures of maternal metabolism obtained during an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyloid Precursor Protein Secretases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aspartic Acid Endopeptidases

Share to Blood Glucose

Share to C-Peptide

Share to Fasting

Share to Genome-Wide Association Study

Share to Glucose Tolerance Test

Share to Pregnancy

Source

Open in PubMed Open full text

Identifiers

PMID: 23903356
DOI: 10.2337/db12-1692
PMCID: PMC3749326

Genes

BACE2
HKDC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of HKDC1 and BACE2 as genes influencing glycemic traits during pregnancy through genome-wide association studies.PMID 23903356Read ↗

Genetics of Gestational Diabetes Mellitus and Maternal Metabolism.Semantic proximity Read ↗

Genetics of glucose homeostasis in pregnancy and postpartum.Semantic proximity Read ↗

Genetic Studies of Gestational Diabetes and Glucose Metabolism in Pregnancy.Semantic proximity Read ↗

Novel insights into the genetic architecture of pregnancy glycemic traits from 14,744 Chinese maternities.Semantic proximity Read ↗

Genetics of Glucose regulation in Gestation and Growth (Gen3G): a prospective prebirth cohort of mother–child pairs in Sherbrooke, CanadaSemantic proximity Read ↗

Multi-ancestry, trans-generational GWAS meta-analysis of gestational diabetes and glycaemic traits during pregnancy reveals limited evidence of pregnancy-specific genetic effects.Semantic proximity Read ↗

Metabolomic and genetic associations with insulin resistance in pregnancy.Semantic proximity Read ↗

Developmental Effects of (Pre-)Gestational Diabetes on Offspring: Systematic Screening Using Omics ApproachesSemantic proximity Read ↗

Targeted Metabolomics Demonstrates Distinct and Overlapping Maternal Metabolites Associated With BMI, Glucose, and Insulin Sensitivity During Pregnancy Across Four Ancestry GroupsSemantic proximity Read ↗

Genetics and Epigenetics: Implications for the Life Course of Gestational DiabetesSemantic proximity Read ↗

DNA Methylation Biomarkers Predict Offspring Metabolic Risk From Mothers With Hyperglycemia in PregnancySemantic proximity Read ↗

Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.