Article
Mitochondrial polymorphisms and dysfunction related to aggressive periodontitis: a pilot study.
Oral diseases - 1 Jul 2014
Wang X, Luan Q, Chen Q, Zhao L, Guo Y
Abstract excerpt
AIM: To investigate whether aggressive periodontitis (AgP) is associated with specific mtDNA polymorphisms or point mutations and furthermore whether mitochondrial dysfunction occurs in gingival fibroblasts of AgP patients. MATERIALS AND METHODS: The mitochondrial DNA coding regions were amplified and sequenced in 22 overlapped fragments in 34 patients with AgP and 28 healthy controls for initial screening. We...
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