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Article

MgrA activates expression of capsule genes, but not the α-toxin gene in experimental Staphylococcus aureus endocarditis.

The Journal of infectious diseases - 1 Dec 2013

Gupta Ravi Kr, Alba Jimena, Xiong Yan Q, Bayer Arnold S, Lee Chia Y

Abstract excerpt

BACKGROUND: Staphylococcus aureus produces numerous virulence factors but little is known about their in vivo regulation during an infection. METHODS: The production of capsule and α-toxin, and the expression of their respective genes, cap5 and hla, were analyzed by comparing CYL11481 (derivative of Newman) and its isogenic regulatory mutants in vitro. The temporal expression of cap5 and hla and the regulatory...

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Identifiers

PMID: 23901087
DOI: 10.1093/infdis/jit367
PMCID: PMC3814835

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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