Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bone formation induced by BMP-2 in human osteosarcoma cells

23 Jul 2013

Abstract excerpt

Our previous studies demonstrated that BMP-2 inhibits the tumorigenicity of cancer stem cells identified as cells with high aldehyde dehydrogenase activity (ALDH(br) cells) from the human osteosarcoma cell line OS99-1. We further investigated whether BMP-2 is capable of inducing bone formation in OS99-1 cells. Flow cytometry sorting was used to isolate tumorigenic ALDH(br) and non-tumorigenic ALDH(lo) cells....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Metabolism and Diseases
Share to Heterotopic Ossification and Related Conditions
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23900689
DOI: 10.3892/ijo.2013.2030

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bone formation induced by BMP-2 in human osteosarcoma cellsPMID 23900689Read ↗

BMP-2 inhibits the tumorigenicity of cancer stem cells in human osteosarcoma OS99-1 cell lineSemantic proximity Read ↗

Osteosarcoma Development and Stem Cell DifferentiationSemantic proximity Read ↗

RUNX2 and OsteosarcomaSemantic proximity Read ↗

Breast cancer cells obtain an osteomimetic feature via epithelial-mesenchymal transition that have undergone BMP2/RUNX2 signaling pathway induction.Semantic proximity Read ↗

Prospective identification of tumorigenic osteosarcoma cancer stem cells in OS99‐1 cells based on high aldehyde dehydrogenase activitySemantic proximity Read ↗

Seven BMPs and all their receptors are simultaneously expressed in osteosarcoma cellsSemantic proximity Read ↗

Investigation of molecular regulators in osteoblast differentiationSemantic proximity Read ↗

Convergence of TGFβ and BMP signaling in regulating human bone marrow stromal cell differentiationSemantic proximity Read ↗

NDUFA4L2 Regulated by HIF-1α Promotes Metastasis and Epithelial–Mesenchymal Transition of Osteosarcoma Cells Through Inhibiting ROS ProductionSemantic proximity Read ↗

Osteoblast-Like Cells in Human Cancers: New Cell Type and Reliable Markers for Bone MetastasisSemantic proximity Read ↗

Runx2 promotes both osteoblastogenesis and novel osteoclastogenic signals in ST2 mesenchymal progenitor cellsSemantic proximity Read ↗

Bone Morphogenetic Protein Signaling in Cancer; Some Topics in the Recent 10 YearsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.