Effect of the functional VEGFA-583C/T variant on vascular endothelial growth factor levels and the risk of recurrent spontaneous miscarriage.

doi:10.1016/j.fertnstert.2011.03.010

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Article

Effect of the functional VEGFA-583C/T variant on vascular endothelial growth factor levels and the risk of recurrent spontaneous miscarriage.

Fertility and sterility - 30 Jun 2011

Al-Khateeb Ghada M, Mustafa Fekriya E, Sater Mai S, Almawi Wassim Y

Abstract excerpt

The association of vascular endothelial growth factor (VEGF) -583C/T variant with recurrent miscarriage (RSM) was investigated in 173 RSM cases and 248 control women. Increased minor allele and genotype frequencies of -583C/T, and reduced serum VEGF concentrations were associated with increased risk of RSM.

Topics

Abortion, Habitual
Adult
Bahrain
Biomarkers
Case-Control Studies
Chi-Square Distribution
Down-Regulation
Female
Genetic Predisposition to Disease
Heterozygote
Homozygote
Humans
Logistic Models
Odds Ratio
Phenotype
Polymorphism, Genetic
Pregnancy
Risk Assessment

Source

Open in PubMed

Identifiers

PMID: 21458805
DOI: 10.1016/j.fertnstert.2011.03.010

Genes

VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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