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Article

Genomic evolution and transmission of <i>Helicobacter pylori</i> in two South African families

29 Jul 2013

Abstract excerpt

Helicobacter pylori infects the stomachs of one in two humans and can cause sequelae that include ulcers and cancer. Here we sequenced the genomes of 97 H. pylori isolates from 52 members of two families living in rural conditions in South Africa. From each of 45 individuals, two H. pylori strains were isolated from the antrum and corpus parts of the stomach, and comparisons of their genomes enabled us to study...

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PMID: 23898187
DOI: 10.1073/pnas.1304681110

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