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Article

MHC variability in an isolated wolf population in Italy.

The Journal of heredity - 1 Jan 2000

Galaverni Marco, Caniglia Romolo, Fabbri Elena, Lapalombella Silvana, Randi Ettore

Abstract excerpt

Small, isolated populations may experience increased extinction risk due to reduced genetic variability at important functional genes, thus decreasing the population's adaptive potential. The major histocompatibility complex (MHC), a key immunological gene cluster, usually shows high variability maintained by positive or balancing selection in response to challenges by pathogens. Here we investigated for the...

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Identifiers

PMID: 23885092
DOI: 10.1093/jhered/est045

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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