Article
Target protein for Xklp2 (TPX2), a microtubule-related protein, contributes to malignant phenotype in bladder carcinoma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Dec 2013
Yan Liang, Li Shenglei, Xu Changbao, Zhao Xinghua, Hao Bin, Li Huixiang, Qiao Baoping
Abstract excerpt
Increasing evidence demonstrated that TPX2 was highly expressed and tightly associated with human tumor development and progression. However, its precise role in bladder carcinoma remains to be delineated. In the present study, we revealed the high expression of TPX2 at both mRNA and protein levels in bladder carcinoma tissues and cells, and TPX2 levels in pN1-3 and pT2-4 status were significantly higher than...
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