Article
Dimer dynamics and filament organization of the bacterial cell division protein FtsA.
Journal of molecular biology - 15 Nov 2013
Hsin Jen, Fu Rui, Huang Kerwyn Casey
Abstract excerpt
FtsA is a bacterial actin homolog and one of the core proteins involved in cell division. While previous studies have demonstrated the capability of FtsA to polymerize, little is known about its polymerization state in vivo or if polymerization is necessary for FtsA function. Given that one function of FtsA is to tether FtsZ filaments to the membrane, in vivo polymerization of FtsA imposes geometric constraints...
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