Article
Impact of genotype on clinical course in arrhythmogenic right ventricular dysplasia/cardiomyopathy-associated mutation carriers.
European heart journal - 7 Apr 2015
Bhonsale Aditya, Groeneweg Judith A, James Cynthia A, Dooijes Dennis, Tichnell Crystal, Jongbloed Jan D H, Murray Brittney, te Riele Anneline S J M, van den Berg Maarten P, Bikker Hennie, Atsma Douwe E, de Groot Natasja M, Houweling Arjan C, van der Heijden Jeroen F, Russell Stuart D, Doevendans Pieter A, van Veen Toon A, Tandri Harikrishna, Wilde Arthur A, Judge Daniel P, van Tintelen J Peter, Calkins Hugh, Hauer Richard N
Abstract excerpt
AIMS: We sought to determine the influence of genotype on clinical course and arrhythmic outcome among arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C)-associated mutation carriers. METHODS AND RESULTS: Pathogenic mutations in desmosomal and non-desmosomal genes were identified in 577 patients (241 families) from USA and Dutch ARVD/C cohorts. Patients with sudden cardiac death (SCD)/ventricular...
Topics
Join the communities discussing this publication.