Article
Constitutive activation of distinct NF-κB signals in EBV-associated nasopharyngeal carcinoma.
The Journal of pathology - 1 Nov 2013
Chung Grace Tin-Yun, Lou Wilson Pak-Kin, Chow Chit, To Ka-Fai, Choy Kwong-Wai, Leung Alice Wan-Chi, Tong Carol Yuen-Kwan, Yuen Jessie Wai-Fong, Ko Chun-Wai, Yip Timothy Tak-Chun, Busson Pierre, Lo Kwok-Wai
Abstract excerpt
As a distinct type of head and neck cancer, non-keratinizing nasopharyngeal carcinoma (NPC) is closely associated with EBV infection and massive lymphoid infiltration. The unique histological features suggest that local inflammation plays an important role in NPC tumourigenesis. We comprehensively characterized NF-κB signalling, a key inflammatory pathway which might contribute to the tumourigenesis of this...
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