Article
Novel deletion in glycoprotein G forms a cluster and causes epidemiologic spread of herpes simplex virus type 2 infection.
Journal of medical virology - 1 Oct 2013
Daikoku Tohru, Horiba Kazuhiro, Kawana Takashi, Hirano Masaru, Shiraki Kimiyasu
Abstract excerpt
The herpes simplex virus type 2 (HSV-2) glycoprotein G (gG-2) gene of 106 clinical isolates was analyzed and six isolates were identified with 63 nucleotides comprising 21 amino acids (aa) deleted in the immunodominant region. Compared with strain HG52, variations in the gG-2 gene were found at 276 and 27 sites in nucleotide and aa sequences, respectively, in the 106 strains. Significant variations in both...
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