Article
Critical evaluation of ASO RQ-PCR for minimal residual disease evaluation in multiple myeloma. A comparative analysis with flow cytometry.
Leukemia - 1 Feb 2014
Puig N, Sarasquete M E, Balanzategui A, Martínez J, Paiva B, García H, Fumero S, Jiménez C, Alcoceba M, Chillón M C, Sebastián E, Marín L, Montalbán M A, Mateos M V, Oriol A, Palomera L, de la Rubia J, Vidriales M B, Bladé J, Lahuerta J J, González M, Miguel J F S, García-Sanz R
Abstract excerpt
We have analyzed the applicability, sensitivity and prognostic value of allele-specific oligonucleotide real-time quantitative PCR (ASO RQ-PCR) as a method for minimal residual disease (MRD) assessment in patients with multiple myeloma (MM), comparing the results with those of multiparameter flow cytometry (MFC). A total of 170 patients enrolled in three consecutive Spanish trials achieving at least partial...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.