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New development in von Willebrand disease

12 Jul 2013

Abstract excerpt

PURPOSE OF REVIEW: Von Willebrand disease (VWD) is an autosomally inherited bleeding disorder caused by a deficiency or abnormality of von Willebrand factor (VWF). VWF is a multimeric adhesive protein produced mainly by the endothelial cells. VWF is crucial in primary hemostasis because it promotes platelet adhesion to the subendothelium at the sites of vascular injury and in coagulation because VWF is the...

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PMID: 23852183
DOI: 10.1097/moh.0b013e328363c11f

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