Article
(R)-nicotine biosynthesis, metabolism and translocation in tobacco as determined by nicotine demethylase mutants.
Phytochemistry - 1 Nov 2013
Cai Bin, Jack Anne M, Lewis Ramsey S, Dewey Ralph E, Bush Lowell P
Abstract excerpt
Nicotine is a chiral compound and consequently exists as two enantiomers. Since (R)-nicotine consists of less than 0.5% of total nicotine pool in tobacco, few investigations relating to (R)-nicotine have been reported. However, previous studies of nicotine demethylases suggested there was substantial amount of (R)-nicotine at synthesis in the tobacco plant. In this study, the accumulation and translocation of...
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