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Article

A eukaryotic molecular target candidate of roxithromycin: fungal differentiation as a sensitive drug target analysis system.

Bioscience, biotechnology, and biochemistry - 1 Jan 2013

Ishii Akira, Kumasaka Mayu, Nagashima Yuka, Nakajima Yuichi, Kuramochi Kouji, Sugawara Fumio, Narukawa Megumi, Kamakura Takashi

Abstract excerpt

Roxithromycin (RXM), active against prokaryotes, has beneficial side effects such as anti-cancer activities on mammalian cells, but the mechanisms underlying these effects remain unclear. We found that RXM inhibited the cellular differentiation of the rice blast fungus Magnaporthe oryzae. Hence,...

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PMID: 23832352
DOI: 10.1271/bbb.130210

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23832352-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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