Article
[The use of the protoplast method for the selection of oleandomycin producers].
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] - 1 Apr 1990
Lavrent'eva G I, Ovsianko A V
Abstract excerpt
The use of protoplasting with subsequent reversion to the cellular form in improvement of the oleandomycin-producing organism provided a 110% increase in the range of culture variation with respect to the antibiotic production property. A regenerant with a potency of 12 to 20 per cent higher than that of the initial strain which produced 30 per cent lower amounts of dark pigments of melanin nature was isolated....
Topics
- Cell Count
- Colony Count, Microbial
- Culture Media
- In Vitro Techniques
- Industrial Microbiology
- Mutation
- Oleandomycin
- Pigments, Biological
- Protoplasts
- Streptomyces