Article
Computational phenotype discovery using unsupervised feature learning over noisy, sparse, and irregular clinical data.
PloS one - 1 Jan 2013
Lasko Thomas A, Denny Joshua C, Levy Mia A
Abstract excerpt
Inferring precise phenotypic patterns from population-scale clinical data is a core computational task in the development of precision, personalized medicine. The traditional approach uses supervised learning, in which an expert designates which patterns to look for (by specifying the learning task and the class labels), and where to look for them (by specifying the input variables). While appropriate for...
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