Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Metabolic Alterations in Mammary Cancer Prevention by Withaferin A in a Clinically Relevant Mouse Model

2 Jul 2013

Abstract excerpt

BACKGROUND: Efficacy of withaferin A (WA), an Ayurvedic medicine constituent, for prevention of mammary cancer and its associated mechanisms were investigated using mouse mammary tumor virus-neu (MMTV-neu) transgenic model. METHODS: Incidence and burden of mammary cancer and pulmonary metastasis were scored in female MMTV-neu mice after 28 weeks of intraperitoneal administration with 100 µg WA (three times/week)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Phytochemicals and Medicinal Plants

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 23821767
DOI: 10.1093/jnci/djt153

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Metabolic Alterations in Mammary Cancer Prevention by Withaferin A in a Clinically Relevant Mouse ModelPMID 23821767Read ↗

Withaferin A decreases glycolytic reprogramming in breast cancerSemantic proximity Read ↗

Withaferin-A—A Natural Anticancer Agent with Pleitropic Mechanisms of ActionSemantic proximity Read ↗

RNA‐seq reveals novel cancer‐selective and disease subtype‐independent mechanistic targets of withaferin A in human breast cancer cellsSemantic proximity Read ↗

Withaferin A suppresses the up‐regulation of acetyl‐coA carboxylase 1 and skin tumor formation in a skin carcinogenesis mouse modelSemantic proximity Read ↗

Molecular insights into cancer therapeutic effects of the dietary medicinal phytochemical withaferin ASemantic proximity Read ↗

2, 3-Dihydro-3β-methoxy Withaferin-A Lacks Anti-Metastasis Potency: Bioinformatics and Experimental EvidencesSemantic proximity Read ↗

Withanolides: Promising candidates for cancer therapySemantic proximity Read ↗

Withanone-Rich Combination of Ashwagandha Withanolides Restricts Metastasis and Angiogenesis through hnRNP-KSemantic proximity Read ↗

Comparative Gene Signature of (−)-Oleocanthal Formulation Treatments in Heterogeneous Triple Negative Breast Tumor Models: Oncological Therapeutic Target InsightsSemantic proximity Read ↗

Adenylate kinase-4 modulates oxidative stress and stabilizes HIF-1α to drive lung cancer metastasisSemantic proximity Read ↗

Differential Activities of the Two Closely Related Withanolides, Withaferin A and Withanone: Bioinformatics and Experimental EvidencesSemantic proximity Read ↗

Ayurvedic Medicine Constituent Withaferin A Causes G2 and M Phase Cell Cycle Arrest in Human Breast Cancer CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.