Article
Evidence for defective Rab GTPase-dependent cargo traffic in immune disorders.
Experimental cell research - 10 Sept 2013
Krzewski Konrad, Cullinane Andrew R
Abstract excerpt
A fully functional immune system is essential to protect the body against pathogens and other diseases, including cancer. Vesicular trafficking provides the correct localization of proteins within all cell types, but this process is most exquisitely controlled and coordinated in immune cells because of their specialized organelles and their requirement to respond to selected stimuli. More than 60 Rab GTPases play...
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