Article
Prevalence of drug resistance mutations and HIV type 1 subtypes in an HIV type 1-infected cohort in rural Tanzania.
AIDS research and human retroviruses - 1 Sept 2013
Masimba Pax, Kituma Elimsaada, Klimkait Thomas, Horvath Edit, Stoeckle Marcel, Hatz Christoph, Mossdorf Erick, Mwaigomole Emmanuel, Khamis Salim, Jullu Boniphace, Abdulla Salim, Tanner Marcel, Felger Ingrid
Abstract excerpt
The development of resistance mutations in drug-targeted HIV-1 genes compromises the success of antiretroviral therapy (ART) programs. Genotyping of these mutations enables adjusted therapeutic decisions both at the individual and population level. We investigated over time the prevalence of HIV-1 primary drug resistance mutations in treatment-naive patients and described the HIV-1 subtype distribution in a...
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