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Article

The methylenetetrahydrofolate reductase C677T polymorphism influences risk of esophageal cancer in Chinese.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013

Qu Hong-Hong, Cui Li-Hong, Wang Ke, Wang Peng, Song Chun-Hua, Wang Kai-Juan, Zhang Jian-Ying, Dai Li-Ping

Abstract excerpt

Methylenetetrahydrofolate reductase (MTHFR) plays a central role in folate metabolism. This study with 381 esophageal cancer patients and 432 healthy controls was conducted to examine the association of MTHFR C677T and A1298C polymorphisms with susceptibility to esophageal cancer (EC) in a Chinese population. Compared with the CC genotype of MTHFR C677T, subjects carrying homozygote TT and variant genotypes...

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Identifiers

PMID: 23803097
DOI: 10.7314/apjcp.2013.14.5.3163

Genes

MTHFR

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