Article
Expression levels of 10 candidate genes in lung tissue of vaccinated and TB-infected cynomolgus macaques.
Journal of medical primatology - 1 Jun 2013
Roodgar Morteza, Lackner Andrew, Kaushal Deepak, Sankaran Sumathi, Dandekar Satya, Trask Jessica Satkoski, Drake Christiana, Smith David Glenn
Abstract excerpt
The expression of ten tuberculosis candidate genes in lung and lymph nodes of cynomolgus macaques vaccinated and experimentally infected with Mycobacterium tuberculosis (Mtb) was quantified. The expression of TNFα, IL10, IL1β, TLR4, IL17, IL6, IL12, and iNOS in the lungs of vaccinated animals was higher than that of non-vaccinated animals.
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