Article
Lack of association of C-Met-N375S sequence variant with lung cancer susceptibility and prognosis.
International journal of medical sciences - 1 Jan 2013
Shieh Jiunn-Min, Tang Yen-An, Yang Tsung-Han, Chen Chih-Yi, Hsu Han-Shui, Tan Yi-Hung Carol, Salgia Ravi, Wang Yi-Ching
Abstract excerpt
BACKGROUND: Previously, we identified a sequence variant (N375S) of c-Met gene, however, its association with lung cancer risk and prognosis remain undefined. PATIENTS AND METHODS: We investigated the genotype distribution of the c-Met-N375S sequence variant in 206 lung cancer patients and 207 non-cancer controls in the Taiwanese population by DNA sequencing. RESULTS: Lung cancer patients with variant A/G and G/G...
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