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Article

ROS-induced autophagy in cancer cells assists in evasion from determinants of immunogenic cell death.

Autophagy - 1 Sept 2013

Garg Abhishek D, Dudek Aleksandra M, Ferreira Gabriela B, Verfaillie Tom, Vandenabeele Peter, Krysko Dmitri V, Mathieu Chantal, Agostinis Patrizia

Abstract excerpt

Calreticulin surface exposure (ecto-CALR), ATP secretion, maturation of dendritic cells (DCs) and stimulation of T cells are prerequisites for anticancer therapy-induced immunogenic cell death (ICD). Recent evidence suggests that chemotherapy-induced autophagy may positively regulate ICD by favoring ATP secretion. We have recently shown that reactive oxygen species (ROS)-based endoplasmic reticulum (ER) stress...

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Source

Identifiers

PMID: 23800749
DOI: 10.4161/auto.25399

Genes

CALR
ATG5
IFNG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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