Article
The 'Red Queen' dilemma--running to stay in the same place: reflections on the evolutionary vector of HBV in humans.
Antiviral therapy - 1 Jan 2013
Tedder Richard S, Bissett Sara L, Myers Richard, Ijaz Samreen
Abstract excerpt
BACKGROUND: Estimates for the evolutionary rate of HBV until now have been interpreted as showing that HBV is a relatively recent acquisition for mankind. The existence of defined HBV genotypes is thought to represent past founder effects. We have explored virus mutation in a group of 48 persistently infected blood donors sampled at two points in time and suggest otherwise. METHODS: HBV-infected donors were...
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