Article
Tumor volume decrease at 8 weeks is associated with longer survival in EGFR-mutant advanced non-small-cell lung cancer patients treated with EGFR TKI.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Aug 2013
Nishino Mizuki, Dahlberg Suzanne E, Cardarella Stephanie, Jackman David M, Rabin Michael S, Hatabu Hiroto, Jänne Pasi A, Johnson Bruce E
Abstract excerpt
BACKGROUND: The study investigated whether tumor volume changes at 8 weeks of therapy is associated with outcomes in advanced non-small-cell lung cancer (NSCLC) patients harboring sensitizing epidermal growth factor receptor (EGFR) mutations treated with EGFR tyrosine kinase inhibitors (TKIs). METHODS: In 56 advanced NSCLC patients with sensitizing EGFR mutations treated with first-line erlotinib or gefitinib,...
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