Article
Microarray analysis of unbalanced translocation in Wolf-Hirschhorn syndrome.
Pediatrics international : official journal of the Japan Pediatric Society - 1 Jun 2013
Dai Ying, Yang Jing, Chen Yuanyuan, Bao Liming, Cheng Qian
Abstract excerpt
Wolf-Hirschhorn syndrome (WHS) is caused by deletions involving chromosome region 4p16.3, which is characterized by growth delay, mild-to-severe mental retardation, hypotonia, facial dysmorphisms and shows extensive phenotypic variability include feeding difficulties, epilepsy and congenital anomalies. Variation in the size of the deletion involving chromosome region 4p16.3 may explain the clinical variation....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.