Article
Longitudinal study on oral shedding of herpes simplex virus 1 and varicella-zoster virus in individuals infected with HIV.
Journal of medical virology - 1 Sept 2013
van Velzen Monique, Ouwendijk Werner J D, Selke Stacy, Pas Suzan D, van Loenen Freek B, Osterhaus Albert D M E, Wald Anna, Verjans Georges M G M
Abstract excerpt
Primary herpes simplex virus 1 (HSV-1) and varicella-zoster virus (VZV) infection leads to a life-long latent infection of ganglia innervating the oral mucosa. HSV-1 and VZV reactivation is more common in immunocompromised individuals and may result in viral shedding in saliva. We determined the kinetics and quantity of oral HSV-1 and VZV shedding in HSV-1 and VZV seropositive individuals infected with HIV and to...
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