Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of a rare haplotype in Kinesin light chain 1 gene with age-related cataract in a han chinese population.

PloS one - 1 Jan 2013

Zhang Lu, Xu Jia-Wei, Qu Xin, Liu Dong-Rui, Liu Ping, Zhao Xin-Zhi

Abstract excerpt

PURPOSE: The causal genes for congenital cataract are good candidates for the genetic susceptibility for age-related cataract (ARC). The aim of this study was to investigate association between the polymorphisms in the causal genes for congenital cataract and ARC in a Chinese population. Meanwhile, we performed the replication study for previous identified risk genes for ARC. METHODS: We recruited 212 sporadic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Alleles
Share to Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cataract

Share to Gene Frequency

Share to Haplotypes

Share to Kinesins

Share to Microtubule-Associated Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 23776437
DOI: 10.1371/journal.pone.0064052
PMCID: PMC3679130

Genes

ARC
KLC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of a rare haplotype in Kinesin light chain 1 gene with age-related cataract in a han chinese population.PMID 23776437Read ↗

The link between apolipoprotein E, presenilin 1, and kinesin light chain 1 gene polymorphisms and age-related cortical cataracts in the Chinese population.Semantic proximity Read ↗

Panel-based targeted exome sequencing reveals novel candidate susceptibility loci for age-related cataracts in Chinese Cohort.Semantic proximity Read ↗

Genetics of human cataract.Semantic proximity Read ↗

Mutations and mechanisms in congenital and age-related cataracts.Semantic proximity Read ↗

Inherited cataracts: molecular genetics, clinical features, disease mechanisms and novel therapeutic approachesSemantic proximity Read ↗

Inherited Congenital Cataract: A Guide to Suspect the Genetic Etiology in the Cataract GenesisSemantic proximity Read ↗

Novel mutations associated with autosomal dominant congenital cataract are identified in Chinese familiesSemantic proximity Read ↗

Novel mutations identified in Chinese families with autosomal dominant congenital cataracts by targeted next-generation sequencing.Semantic proximity Read ↗

Integrative multi-omics quantitative trait loci prioritize CASP7 as a candidate protective gene for cataract.Semantic proximity Read ↗

Uncovering Novel Genetic Loci and Biological Pathways Associated with Age-Related Cataracts through GWAS Meta-AnalysisSemantic proximity Read ↗

Inherited cataracts: Genetic mechanisms and pathways new and old.Semantic proximity Read ↗

Polymorphism rs7278468 is associated with Age-related cataract through decreasing transcriptional activity of the CRYAA promoter.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.