Article
Gender dimorphism in regulation of plasma proteins in streptozotocin-induced diabetic rats.
Proteomics - 1 Aug 2013
Choi Jung-Won, Aseer Kanikkai Raja, Chaudhari Harmesh N, Mukherjee Rajib, Choi Minji, Yun Jong Won
Abstract excerpt
In the present study, we examined differentially regulated plasma proteins between healthy control and streptozotocin (STZ)-induced male and female diabetic rats by 2DE-based proteomic analysis. Animal experiments revealed that significantly lower plasma insulin levels were observed in female diabetic rats, consequently resulting in higher blood glucose levels in female diabetic rats. Importantly, plasma levels...
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