Article
Association of cell adhesion molecule gene polymorphisms with recurrent aphthous stomatitis.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Nov 2013
Alkhateeb Asem, Karasneh Jumana, Abbadi Hebah, Hassan Ahmad, Thornhill Martin
Abstract excerpt
BACKGROUND: Recurrent aphthous stomatitis (RAS) is a common oral ulcerative condition. At ulcer sites vascular adhesion molecule-1 (VCAM-1), E-selectin and intercellular adhesion molecule-1 (ICAM-1) are strongly expressed on blood vessels, and ICAM-1 is expressed on keratinocytes. Expression of these molecules would promote leukocyte accumulation and invasion of the epithelium. Thus, polymorphisms in these...
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