Article
Genetic analysis through OtoSeq of Pakistani families segregating prelingual hearing loss.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery - 1 Sept 2013
Shahzad Mohsin, Sivakumaran Theru A, Qaiser Tanveer A, Schultz Julie M, Hussain Zawar, Flanagan Megan, Bhinder Munir A, Kissell Diane, Greinwald John H, Khan Shaheen N, Friedman Thomas B, Zhang Kejian, Riazuddin Saima, Riazuddin Sheikh, Ahmed Zubair M
Abstract excerpt
OBJECTIVE: To identify the genetic cause of prelingual sensorineural hearing loss in Pakistani families using a next-generation sequencing (NGS)-based mutation screening test named OtoSeq. STUDY DESIGN: Prospective study. SETTING: Research laboratory. SUBJECTS AND METHODS: We used 3 fluorescently labeled short tandem repeat (STR) markers for each of the known autosomal recessive nonsyndromic (DFNB) and Usher...
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